Located in Los Angeles (Downtown Los Angeles), USC Hotel is within a 10-minute walk of Shrine Auditorium and University of Southern California. This hotel is 1.1 mi (1.8 km) from California Science Center and 1.4 mi (2.3 km) from Los Angeles Memorial Coliseum.

Make yourself at home in one of the 240 air-conditioned rooms featuring refrigerators and LCD televisions. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers. Conveniences include safes and desks, and housekeeping is provided daily.

Take advantage of recreational opportunities offered, including an outdoor pool, a spa tub, and a 24-hour fitness center. This hotel also features complimentary wireless Internet access, concierge services, and gift shops/newsstands.

Grab a bite at McKays Restaurant, one of the hotel's 3 restaurants, or stay in and take advantage of the room service (during limited hours). Snacks are also available at the coffee shop/café. Wrap up your day with a drink at the bar/lounge. Buffet breakfasts are available daily from 7 AM to 10 AM for a fee.

Featured amenities include a 24-hour business center, express check-out, and complimentary newspapers in the lobby. Event facilities at this hotel consist of conference space and meeting rooms. Self parking (subject to charges) is available onsite.