MOXY Berlin Humboldthain Park is located in Mitte District of Berlin's city center, the hotel is just steps from Bahnhof Gesundbrunnen train station. The Berlin Zoo, Brandenburg Gate, Alexanderplatz, Charlottenburg Palace, Humboldthain Park and Prenzlauer Berg are all accessible from the hotel's city centre location in Mitte, Berlin.

The hotel has a restaurant and bar.

Rooms and suites offer amenities like 43-inch TVs, walk-in showers, leather furniture and complimentary high-speed Wi-Fi access.